BDBM558186 7-[[6-(1H-Pyrazol-5-yl)-3-pyridinyl]oxymethyl]-5,6,7,8-tetrahydronaphthalene-2-carboxylic Acid::US11365192, Example 5-1

SMILES OC(=O)c1ccc2CCC(COc3ccc(nc3)-c3ccn[nH]3)Cc2c1

InChI Key InChIKey=QBPDWPZXVCZWAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 558186   

TargetCytochrome P450 4F2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558186(US11365192, Example 5-1 | 7-[[6-(1H-Pyrazol-5-yl)-...)
Affinity DataIC50: 33nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetCytochrome P450 4A11(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558186(US11365192, Example 5-1 | 7-[[6-(1H-Pyrazol-5-yl)-...)
Affinity DataIC50: 22nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent