BDBM558166 US11365192, Example 2-1::trans-4-[[6-(1H-Pyrazol-5-yl)-3-pyridinyl]oxymethyl]-1-adamantanecarboxylic Acid

SMILES OC(=O)[C@@]12CC3C[C@@H](C1)[C@@H](COc1ccc(nc1)-c1ccn[nH]1)[C@H](C3)C2

InChI Key InChIKey=DKWHALMUYYGXAZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 558166   

TargetCytochrome P450 4F2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558166(US11365192, Example 2-1 | trans-4-[[6-(1H-Pyrazol-...)
Affinity DataIC50: 2.40E+4nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetCytochrome P450 4A11(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558166(US11365192, Example 2-1 | trans-4-[[6-(1H-Pyrazol-...)
Affinity DataIC50: 23nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent