BDBM557869 1-(3-((4-((3-cyclopropyl- phenyl)amino)-7-methoxy- quinazolin-6-yl)oxy)- azetidin-1-yl)prop-2-en-1- one::US11365189, Ex. No. 31
SMILES COc1cc2ncnc(Nc3cccc(c3)C3CC3)c2cc1OC1CN(C1)C(=O)C=C
InChI Key InChIKey=SRIGNLHWFILXLC-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 557869
TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255](Human)
University Of Texas
US Patent
University Of Texas
US Patent
Affinity DataIC50: 600nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2 [1-780,'GSP',781-1255](Human)
University Of Texas
US Patent
University Of Texas
US Patent
Affinity DataIC50: 79nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'VC',777-1255](Human)
University Of Texas
US Patent
University Of Texas
US Patent
Affinity DataIC50: 160nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair