BDBM557674 US11358953, Example 11

SMILES CC1(C)[C@@H]2CN([C@@H]([C@H]12)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N)C(=O)c1cc2c(OC(F)F)cccc2[nH]1

InChI Key InChIKey=YCSCOAGMDRJISW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 557674   

TargetReplicase polyprotein 1a(2019-nCoV)
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM557674(US11358953, Example 11)
Affinity DataIC50: 550nMAssay Description:SARS-CoV-2 3C-like (3CL) protease fluorescence assay (FRET): Recombinant SARS-CoV-2 3CL-protease was expressed and purified. TAMRA-SITSAVLQSGFRKMK-Da...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2022
Entry Details
Go to US Patent