BDBM557265 US11352354, Example V-c-17

SMILES COc1ccc(cc1Nc1nc(-c2cccnc2)c2[nH]ccc2n1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=WBGATGVPZVAVOT-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 557265   

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557265(US11352354, Example V-c-17)
Affinity DataKd:  6.40E+5nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Xiamen University

US Patent
LigandPNGBDBM557265(US11352354, Example V-c-17)
Affinity DataKd:  6.40nMAssay Description:Binding affinity to PIKFYVE (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed