BDBM554717 US11339144, Compound I-167

SMILES CC(C)(C)OC(=O)c1ccc(Cn2c(cc3c(Br)cc(Oc4ccccc4)cc23)C(O)=O)cc1

InChI Key InChIKey=BXNCERMCCHSMHJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554717   

TargetGTP-binding protein Rheb(Human)
Navitor Pharmaceuticals

US Patent
LigandPNGBDBM554717(US11339144, Compound I-167)
Affinity DataIC50: 1.00E+4nMAssay Description:For the Rheb-dependent in vitro kinase assay, HA-GST-Rheb was first loaded with GTP-γ-S (Millipore #20-176) by incubating 600 ng/μL Rheb wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
Go to US Patent