BDBM554525 (5RS)-2-{[3-Chloro-4-(trifluoromethyl)pyridin-2-yl]methyl}-5-{[(3S)-3-fluoropyrrolidin-1-yl]carbonyl}-7-isobutyl-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazin-3(2H)-one (Diastereomer Mixture; 2 Isomers)::US11337973, Example 29
SMILES CC(C)CN1CC(C(=O)N2CC[C@H](F)C2)n2c(C1)nn(Cc1nccc(c1Cl)C(F)(F)F)c2=O
InChI Key InChIKey=OBOHPPITJBNRRT-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 554525
Affinity DataIC50: 2.40nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair