BDBM554513 (5RS)-2-(4-Methylbenzyl)-3-oxo-5-(pyrrolidin-1-ylcarbonyl)-N-(2,2,2-trifluoroethyl)-2,5,6,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine-7(3H)-carboxamide (Racemate)::US11337973, Example 17

SMILES Cc1ccc(Cn2nc3CN(CC(C(=O)N4CCCC4)n3c2=O)C(=O)NCC(F)(F)F)cc1

InChI Key InChIKey=CBRXTUCRWZIIOJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554513   

TargetProlyl endopeptidase(Human)
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US Patent
LigandPNGBDBM554513((5RS)-2-(4-Methylbenzyl)-3-oxo-5-(pyrrolidin-1-ylc...)
Affinity DataIC50: 0.160nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
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Date in BDB:
8/28/2022
Entry Details
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