BDBM554367 US11332451, Compound I-23::US11377428, Compound I-23

SMILES CN1c2cc(\C=C\C(=O)NC3CC3)ccc2OC[C@H](NC(=O)c2n[nH]c(Cc3ccccc3)n2)C1=O

InChI Key InChIKey=VJMGLVIZONULSM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 554367   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM554367(US11377428, Compound I-23 | US11332451, Compound I...)
Affinity DataIC50: 35.2nMAssay Description:A 500 ml stock volume of 5× Reaction Kinase Buffer was made by mixing 1000 μl of 1M MgCl2, 500 μl of 1M Tris-HCL pH7.4, 0.5 mg/ml (25 mg) o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM554367(US11377428, Compound I-23 | US11332451, Compound I...)
Affinity DataIC50: 35.2nMAssay Description:A 500 ml stock volume of 5× Reaction Kinase Buffer was made by mixing 1000 μl of 1M MgCl2, 500 μl of 1M Tris-HCL pH7.4, 0.5 mg/ml (25 mg) o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent