BDBM552043 US11312726, Compound 14

SMILES Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)Nc1ccc3C[S@](=O)Cc3c1)c1nnc(C)n-21)c1ccc(Cl)cc1

InChI Key InChIKey=KUGCXAUOOXWBRU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 552043   

TargetBromodomain-containing protein 4 [44-167](Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM552043(US11312726, Compound 14)
Affinity DataIC50: 69nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [349-460](Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM552043(US11312726, Compound 14)
Affinity DataIC50: 8nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent