BDBM551734 US11312722, Compound 24

SMILES COc1ccc(Cn2nc(C)cc2Nc2cc(O)cc(O)c2C(=O)N2Cc3cn[nH]c3C2)cc1

InChI Key InChIKey=PKJZRNPLOBZLOL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551734   

TargetHsp90 chaperone protein kinase-targeting subunit(Cryptococcus neoformans var. neoformans serotype D...)
Trustees of Boston University

US Patent
LigandPNGBDBM551734(US11312722, Compound 24)
Affinity DataEC50:  63nMAssay Description:EC50 values were determined by FP-based equilibrium competition assay performed in 384-well format using whole cell lysates prepared from C. neoforma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent

TargetHeat shock protein 90 homolog(Yeast)
Trustees of Boston University

US Patent
LigandPNGBDBM551734(US11312722, Compound 24)
Affinity DataEC50:  157nMAssay Description:EC50 values were determined by FP-based equilibrium competition assay performed in 384-well format using whole cell lysates prepared from C. neoforma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent