BDBM551434 6-(7-methoxy-9H-pyrrolo[2,3-b: 4,5-c']dipyridin-2-yl)-::US11312716, Example 40

SMILES CNC(=O)c1ccc(nc1)-c1ccc2c(n1)[nH]c1cc(OC)ncc21

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551434   

TargetMicrotubule-associated protein tau(Human)
Ucb Biopharma

US Patent
LigandPNGBDBM551434(6-(7-methoxy-9H-pyrrolo[2,3-b: 4,5-c']dipyridin-2-...)
Affinity DataIC50: 39.8nMAssay Description:[3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent