BDBM551077 2,5-Bis(trifluoromethyl)-3-(7-vinyl-1H-indazol-5-yl)-3H-imidazo[4,5-b]pyridine;::US11312712, Example 189

SMILES FC(F)(F)c1nc2ccc(nc2n1-c1cc(C=C)c2[nH]ncc2c1)C(F)(F)F

InChI Key InChIKey=IYYPWGWNMOEALZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551077   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM551077(2,5-Bis(trifluoromethyl)-3-(7-vinyl-1H-indazol-5-y...)
Affinity DataIC50: 0.0400nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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