BDBM55082 N-[4-[(2-chlorobenzoyl)amino]-3-methoxy-phenyl]picolinamide::N-[4-[(2-chlorobenzoyl)amino]-3-methoxyphenyl]pyridine-2-carboxamide::N-[4-[(2-chlorophenyl)carbonylamino]-3-methoxy-phenyl]pyridine-2-carboxamide::N-[4-[[(2-chlorophenyl)-oxomethyl]amino]-3-methoxyphenyl]-2-pyridinecarboxamide::VU0415374-1::cid_46869940

SMILES COc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccccc1Cl

InChI Key InChIKey=RZZCVJKQCRSTKD-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 55082   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM55082(VU0415374-1 | N-[4-[[(2-chlorophenyl)-oxomethyl]am...)
Affinity DataEC50:  95.3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetMetabotropic glutamate receptor 4 [Q124R](Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM55082(VU0415374-1 | N-[4-[[(2-chlorophenyl)-oxomethyl]am...)
Affinity DataEC50:  110nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM55082(VU0415374-1 | N-[4-[[(2-chlorophenyl)-oxomethyl]am...)
Affinity DataEC50:  99.5nMAssay Description:Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55082(VU0415374-1 | N-[4-[[(2-chlorophenyl)-oxomethyl]am...)
Affinity DataEC50:  106nMAssay Description:Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55082(VU0415374-1 | N-[4-[[(2-chlorophenyl)-oxomethyl]am...)
Affinity DataEC50:  34nMAssay Description:Positive allosteric modulation of rat mGlu4 receptor expressed in HEK293 cells coexpressing GIRK assessed as thallium influx in presence of EC20 glut...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed