BDBM550664 8′-Methyl-6′-({6-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]hept-5-ylcarbonyl]thieno[2,3-d]pyrimidin-4-yl}amino)-2′H-spiro[cyclobutane-1,3′-imidazo[1,5-a]pyridine]-1′,5′-dione::US11311520, Example 158

SMILES Cc1cc(Nc2ncnc3sc(cc23)C(=O)N2C[C@@]3([W])C[C@@H]2CO3)c(=O)n2c1C(=O)NC21CCC1

InChI Key InChIKey=CZECBMBKFRUPPX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550664   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM550664(8′-Methyl-6′-({6-[(1R,4R)-2-oxa-5-azab...)
Affinity DataIC50: 5nMAssay Description:MKNK1-inhibitory activity at high ATP of compounds of the present invention after their preincubation with MKNK1 was quantified employing the TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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