BDBM550565 N-[2-(Dimethylamino)ethyl]-4-[(8′-methyl-1′,5′-dioxo-1′,5′-dihydro-2′H-spiro[cyclopentane-1,3′-imidazo[1,5-a]pyridin]-6′-yl)amino]thieno[2,3-d]pyrimidine-6-carboxamide::US11311520, Example 59

SMILES CN(C)CCNC(=O)c1cc2c(Nc3cc(C)c4C(=O)NC5(CCCC5)n4c3=O)ncnc2s1

InChI Key InChIKey=AOGJPMOEFHRZEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550565   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM550565(N-[2-(Dimethylamino)ethyl]-4-[(8′-methyl-1&#...)
Affinity DataIC50: 2.70nMAssay Description:MKNK1-inhibitory activity at high ATP of compounds of the present invention after their preincubation with MKNK1 was quantified employing the TR-FRET...More data for this Ligand-Target Pair
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Date in BDB:
8/6/2022
Entry Details
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