BDBM550504 US11306105, Compound 208

SMILES C[C@@H](O)CNC(=O)C[C@@H]1N=C(c2c(C)c(CC#N)sc2-n2c(C)nnc12)c1ccc(Cl)cc1

InChI Key InChIKey=DHZQOSMBNJKSCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 550504   

TargetBromodomain testis-specific protein [22-138](Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550504(US11306105, Compound 208)
Affinity DataIC50: 1.20E+3nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2022
Entry Details
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TargetBromodomain-containing protein 4 [44-167](Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550504(US11306105, Compound 208)
Affinity DataIC50: 415nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2022
Entry Details
Go to US Patent