BDBM550491 US11306105, Compound 107

SMILES C[C@H](O)CNC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(cc1)C#N

InChI Key InChIKey=CAKYNETUOQZPMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 550491   

TargetBromodomain testis-specific protein [22-138](Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550491(US11306105, Compound 107)
Affinity DataIC50: 187nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-167](Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550491(US11306105, Compound 107)
Affinity DataIC50: 61nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2022
Entry Details
Go to US Patent