BDBM550441 US11306098, Example 8::US11583538, Example 9

SMILES CC(C)C[C@@H](N1CCC(CCc2ccccc2)N2C[C@H](N)C[C@H]2C1=O)C(=O)NCc1ccccc1

InChI Key InChIKey=LDQLHRDRBWQIKA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 550441   

TargetThree-prime repair exonuclease 1(Human)
Venenum Biodesign

US Patent
LigandPNGBDBM550441(US11583538, Example 9 | US11306098, Example 8)
Affinity DataIC50: 5.50E+3nMAssay Description:To evaluate the effect of compounds on TREX1 activity, test compounds were serially diluted (11-point, 3-fold) from 10 mM stock solutions and deliver...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThree-prime repair exonuclease 1(Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM550441(US11583538, Example 9 | US11306098, Example 8)
Affinity DataIC50: 5.50E+4nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetThree-prime repair exonuclease 1(Human)
Venenum Biodesign

US Patent
LigandPNGBDBM550441(US11583538, Example 9 | US11306098, Example 8)
Affinity DataIC50: 5.50E+3nMAssay Description:For human TREX1, the nucleotide sequence of the gene construct was codon optimized for expression in the bacterial host. The sequence was incorporate...More data for this Ligand-Target Pair
In DepthDetails
US Patent