BDBM5482 1-[(2-amino-9H-purin-6-yl)oxy]-3-methylbutan-2-one::CHEMBL272690::O6-Substituted Guanine Deriv. 22

SMILES CC(C)C(=O)COc1nc(N)nc2nc[nH]c12

InChI Key InChIKey=BEXUQVHWMLPYKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5482   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
University of Newcastle

LigandPNGBDBM5482(1-[(2-amino-9H-purin-6-yl)oxy]-3-methylbutan-2-one...)
Affinity DataAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Human)
University of Newcastle

LigandPNGBDBM5482(1-[(2-amino-9H-purin-6-yl)oxy]-3-methylbutan-2-one...)
Affinity DataAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5482(1-[(2-amino-9H-purin-6-yl)oxy]-3-methylbutan-2-one...)
Affinity DataIC50: 1.00E+6nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in HT-29 cell extract.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed