BDBM54712 1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-[5-(4-methoxyphenyl)-2-furanyl]-1-propanone::1-[4-(2,5-dimethylphenyl)piperazin-1-yl]-3-[5-(4-methoxyphenyl)furan-2-yl]propan-1-one::1-[4-(2,5-dimethylphenyl)piperazino]-3-[5-(4-methoxyphenyl)-2-furyl]propan-1-one::KUC103447N::UNM-0000306164::cid_44193698

SMILES COc1ccc(cc1)-c1ccc(CCC(=O)N2CCN(CC2)c2cc(C)ccc2C)o1

InChI Key InChIKey=OYLZQIGMHXBFJW-UHFFFAOYSA-N

Data  1 KI  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 54712   

LigandPNGBDBM54712(KUC103447N | 1-[4-(2,5-dimethylphenyl)piperazin-1-...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGTPase KRas [1-37](Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54712(KUC103447N | 1-[4-(2,5-dimethylphenyl)piperazin-1-...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM54712(KUC103447N | 1-[4-(2,5-dimethylphenyl)piperazin-1-...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetRas-related protein Rab-7a(Dog)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54712(KUC103447N | 1-[4-(2,5-dimethylphenyl)piperazin-1-...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetRas-related protein Rab-2A(Dog)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54712(KUC103447N | 1-[4-(2,5-dimethylphenyl)piperazin-1-...)
Affinity DataEC50:  1.51E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM54712(KUC103447N | 1-[4-(2,5-dimethylphenyl)piperazin-1-...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGTPase KRas [1-37](Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54712(KUC103447N | 1-[4-(2,5-dimethylphenyl)piperazin-1-...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM54712(KUC103447N | 1-[4-(2,5-dimethylphenyl)piperazin-1-...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetRas-related protein Rab-2A(Dog)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54712(KUC103447N | 1-[4-(2,5-dimethylphenyl)piperazin-1-...)
Affinity DataKi:  960nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay