BDBM542455 6-[2-(3-amino-5-fluoro-1-piperidyl)-4-(4-fluorophenyl) cyclopentoxy]-5-methyl-pyridazine-3-carbonitrile::US11274091, Example 22

SMILES Cc1cc(nnc1OC1CC(CC1N1CC(N)CC(F)C1)c1ccc(F)cc1)C#N

InChI Key InChIKey=YWCKBHDCKIOOJA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 542455   

TargetShort transient receptor potential channel 6(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM542455(6-[2-(3-amino-5-fluoro-1-piperidyl)-4-(4-fluorophe...)
Affinity DataIC50: 28.8nMAssay Description:For TRPC6 current recording, the intracellular solution contained (in mM): 120 CsOH, 120 Aspartate, 20 CsCl, 2 MgCl2, 0.4 CaCl2, 10 HEPES, 2 Na2ATP, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetShort transient receptor potential channel 3(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM542455(6-[2-(3-amino-5-fluoro-1-piperidyl)-4-(4-fluorophe...)
Affinity DataIC50: 118nMAssay Description:For TRPC6 current recording, the intracellular solution contained (in mM): 120 CsOH, 120 Aspartate, 20 CsCl, 2 MgCl2, 0.4 CaCl2, 10 HEPES, 2 Na2ATP, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent