BDBM542443 5-fluoro-1-[4-(4-fluorophenyl)-2-(1,2,4-triazol-1-yl) cyclopentyl]piperidin-3-amine::US11274091, Example 10

SMILES N[C@@H]1C[C@@H](F)CN(C1)[C@@H]1C[C@@H](C[C@H]1n1cncn1)c1ccc(F)cc1

InChI Key InChIKey=ATVWXELBUSAQIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 542443   

TargetShort transient receptor potential channel 6(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM542443(5-fluoro-1-[4-(4-fluorophenyl)-2-(1,2,4-triazol-1-...)
Affinity DataIC50: 29.8nMAssay Description:For TRPC6 current recording, the intracellular solution contained (in mM): 120 CsOH, 120 Aspartate, 20 CsCl, 2 MgCl2, 0.4 CaCl2, 10 HEPES, 2 Na2ATP, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetShort transient receptor potential channel 3(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM542443(5-fluoro-1-[4-(4-fluorophenyl)-2-(1,2,4-triazol-1-...)
Affinity DataIC50: 16nMAssay Description:For TRPC6 current recording, the intracellular solution contained (in mM): 120 CsOH, 120 Aspartate, 20 CsCl, 2 MgCl2, 0.4 CaCl2, 10 HEPES, 2 Na2ATP, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent