BDBM542439 5-fluoro-1-[4-(4-fluorophenyl)-2-pyrazol-1-yl-cyclopentyl] piperidin-3-amine::US11274091, Example 9

SMILES NC1CC(F)CN(C1)C1CC(CC1n1cccn1)c1ccc(F)cc1

InChI Key InChIKey=YYBCNHLZAHJUAY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 542439   

TargetShort transient receptor potential channel 6(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM542439(5-fluoro-1-[4-(4-fluorophenyl)-2-pyrazol-1-yl-cycl...)
Affinity DataIC50: 3.40nMAssay Description:For TRPC6 current recording, the intracellular solution contained (in mM): 120 CsOH, 120 Aspartate, 20 CsCl, 2 MgCl2, 0.4 CaCl2, 10 HEPES, 2 Na2ATP, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetShort transient receptor potential channel 3(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM542439(5-fluoro-1-[4-(4-fluorophenyl)-2-pyrazol-1-yl-cycl...)
Affinity DataIC50: 6.64nMAssay Description:For TRPC6 current recording, the intracellular solution contained (in mM): 120 CsOH, 120 Aspartate, 20 CsCl, 2 MgCl2, 0.4 CaCl2, 10 HEPES, 2 Na2ATP, ...More data for this Ligand-Target Pair
In DepthDetails
US Patent