BDBM541726 US11267811, Example A56

SMILES Cc1nc([C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cc(F)c3ccccc3c2)n(n1)-c1cc(Cl)ccc1C(F)(F)F

InChI Key InChIKey=MNCXEEAEYSCLPA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 541726   

TargetGalectin-3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM541726(US11267811, Example A56)
Affinity DataIC50: 32nMAssay Description:The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGalectin-3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM541726(US11267811, Example A56)
Affinity DataIC50: 32nMAssay Description:Inhibition of His-tagged recombinant human Gal-3 preincubated for 30 mins followed by B-ASF addition measured after 1 hr by time resolved fluorescenc...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGalectin-3(Mouse)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM541726(US11267811, Example A56)
Affinity DataIC50: 183nMAssay Description:Inhibition of His-tagged recombinant mouse Gal-3 preincubated for 30 mins followed by B-ASF addition measured after 1 hr by time resolved fluorescenc...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGalectin-1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM541726(US11267811, Example A56)
Affinity DataIC50: 3.65E+3nMAssay Description:Inhibition of His-tagged recombinant human Gal-1 preincubated for 30 mins followed by B-ASF addition measured after 1 hr by time resolved fluorescenc...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGalectin-9(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM541726(US11267811, Example A56)
Affinity DataIC50: 6.11E+3nMAssay Description:Inhibition of His-tagged recombinant human Gal-9 preincubated for 30 mins followed by B-ASF addition measured after 1 hr by time resolved fluorescenc...More data for this Ligand-Target Pair
In DepthDetails
PubMed