BDBM53935 4-methyl-N-[(5Z)-4-oxidanylidene-5-(phenylmethylidene)-1,3-thiazol-2-yl]benzenesulfonamide::4-methyl-N-[(5Z)-4-oxo-5-(phenylmethylene)-2-thiazolyl]benzenesulfonamide::MLS000676644::N-(5-benzylidene-4-oxo-4,5-dihydro-1,3-thiazol-2-yl)-4-methylbenzenesulfonamide::N-[(5Z)-5-benzal-4-keto-2-thiazolin-2-yl]-4-methyl-benzenesulfonamide::N-[(5Z)-5-benzylidene-4-oxo-1,3-thiazol-2-yl]-4-methylbenzenesulfonamide::SMR000298295::cid_1911572

SMILES Cc1ccc(cc1)S(=O)(=O)NC1=NC(=O)\C(S1)=C\c1ccccc1

InChI Key InChIKey=MQJNUABGJUASJP-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 53935   

TargetM1 family aminopeptidase(Plasmodium falciparum (isolate FcB1 / Columbia))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM53935(4-methyl-N-[(5Z)-4-oxo-5-(phenylmethylene)-2-thiaz...)
Affinity DataIC50: 6.92E+4nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2011
Entry Details
PCBioAssay
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53935(4-methyl-N-[(5Z)-4-oxo-5-(phenylmethylene)-2-thiaz...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetCorticotropin-releasing factor-binding protein(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53935(4-methyl-N-[(5Z)-4-oxo-5-(phenylmethylene)-2-thiaz...)
Affinity DataEC50: >5.30E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetCorticotropin-releasing factor-binding protein(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53935(4-methyl-N-[(5Z)-4-oxo-5-(phenylmethylene)-2-thiaz...)
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHuntingtin(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM53935(4-methyl-N-[(5Z)-4-oxo-5-(phenylmethylene)-2-thiaz...)
Affinity DataIC50: 879nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay