BDBM538098 US11248013, Example 59

SMILES OC(c1ccc(F)c(c1)P1(=O)CCN(CC1)c1ncccn1)c1n[nH]c(=O)c2ccccc12

InChI Key InChIKey=FZJVXOBGMQGVHJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 538098   

TargetPoly [ADP-ribose] polymerase 1(Human)
Rakovina Therapeutics

US Patent
LigandPNGBDBM538098(US11248013, Example 59)
Affinity DataIC50: 100nMAssay Description:Inhibition of PARP-1 enzymatic activities was measured using an HT Universal Colorimetric PARP Assay Kit (Trevigen, catalogue #4677-096-K) following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
Go to US Patent