BDBM538090 4-[[4-fluoro-3-(4-ethyl-4-oxo-1,4- azaphosphinane-1-carbonyl)phenyl]methyl]- 2H-phthalazin-1-one::US11248013, Example 51

SMILES CCP1(=O)CCN(CC1)C(=O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F

InChI Key InChIKey=ZGNPQBZYKKGONQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 538090   

TargetPoly [ADP-ribose] polymerase 1(Human)
Rakovina Therapeutics

US Patent
LigandPNGBDBM538090(4-[[4-fluoro-3-(4-ethyl-4-oxo-1,4- azaphosphinane-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of PARP-1 enzymatic activities was measured using an HT Universal Colorimetric PARP Assay Kit (Trevigen, catalogue #4677-096-K) following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
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