BDBM537962 US11248001, Example 493::US11603523, Example 493

SMILES Clc1cnc(N[C@H]2CC[C@@H](C2)Nc2ccc(cn2)-n2ccccc2=O)nc1

InChI Key InChIKey=MONCSLBNMBXWBY-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 537962   

TargetProprotein convertase subtilisin/kexin type 9(Human)
Astrazeneca

US Patent
LigandPNGBDBM537962(US11248001, Example 493 | US11603523, Example 493)
Affinity DataKd: <200nMAssay Description:Surface plasmon resonance data was collected on a Biacore T200 or 3000 system (GE Healthcare) at 25° C. Streptavidin was immobilized on a CMS (GE Hea...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProprotein convertase subtilisin/kexin type 9(Human)
Astrazeneca

US Patent
LigandPNGBDBM537962(US11248001, Example 493 | US11603523, Example 493)
Affinity DataKd: <200nMAssay Description:Surface plasmon resonance data was collected on a Biacore T200 or 3000 system (GE Healthcare) at 25° C. Streptavidin was immobilized on a CM5 (GE Hea...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProprotein convertase subtilisin/kexin type 9(Human)
Astrazeneca

US Patent
LigandPNGBDBM537962(US11248001, Example 493 | US11603523, Example 493)
Affinity DataKd: <200nMAssay Description:Inhibition of human recombinant Avi-tagged PCSK9 assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed