BDBM536513 (S)-7-(1-(2-((3-chloro- 6-(2,4-dimethylpipera- zin-1-yl)-2-fluoro- pyridin-4-yl)amino)-2- oxoethyl)-7,7-dimethyl- 4-oxo-4,6,7,8-tetra- hydro-1H-dipyrrolo [1,2-a:2',3'-d]pyrimi- din-3-yl)-4-hydroxy- benzo[d][1,3]dioxole- 5-carboxamide::US11242351, Compound I-92

SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2nc2CC(C)(C)Cn2c3=O)c(Cl)c(F)n1

InChI Key InChIKey=BVDIOLYYCUETLL-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536513   

TargetB-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429](Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandPNGBDBM536513((S)-7-(1-(2-((3-chloro- 6-(2,4-dimethylpipera- zin...)
Affinity DataKd:  0.870nMAssay Description:This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent