BDBM536509 7-(1-(2-((5-chloro-2- ((S)-3-methylmorpho- lino)pyridin-4-yl) amino)-2-oxoethyl)- 7-methyl-4-oxo- 4,6,7,8-tetrahydro-1H- dipyrrolo[1,2-a:2',3'-d] pyrimidin-3-yl)-4- hydroxybenzo[d][1,3] dioxole-5-carboxamide::US11242351, Compound I-88

SMILES CC1Cc2nc3n(CC(=O)Nc4cc(ncc4Cl)N4CCOC[C@@H]4C)cc(-c4cc(C(N)=O)c(O)c5OCOc45)c3c(=O)n2C1

InChI Key InChIKey=YPRPACRVACWNDH-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536509   

TargetB-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429](Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandPNGBDBM536509(7-(1-(2-((5-chloro-2- ((S)-3-methylmorpho- lino)py...)
Affinity DataKd:  2.14nMAssay Description:This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent