BDBM536499 5-(1-(2-((3-chloro-6- ((S)-2,4-dimethyl- piperazin-1-yl)-2- fluoropyridin-4-yl) amino)-2-oxoethyl)- 7-methyl-4-oxo- 4,6,7,8-tetrahydro-1H- dipyrrolo[1,2-a:2',3'-d] pyrimidin-3-yl)-3- fluoro-2-hydroxy- benzamide::US11242351, Compound I-78

SMILES CC1Cc2nc3n(CC(=O)Nc4cc(nc(F)c4Cl)N4CCN(C)C[C@@H]4C)cc(-c4cc(F)c(O)c(c4)C(N)=O)c3c(=O)n2C1

InChI Key InChIKey=CQGRFRUEBSJQLD-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536499   

TargetB-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429](Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandPNGBDBM536499(5-(1-(2-((3-chloro-6- ((S)-2,4-dimethyl- piperazin...)
Affinity DataKd:  2.03nMAssay Description:This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent