BDBM536496 (S)-3-chloro-5-(1-(2- ((3-chloro-2-fluoro-6- (4-(2-methoxyethyl)- 2-methylpiperazin-1- yl)pyridin-4-yl) amino)-2-oxoethyl)- 4-oxo-4,6,7,8-tetra- hydro-1H-dipyrrolo [1,2-a:2',3'-d]pyrimi- din-3-yl)-2-hydroxy- benzamide::US11242351, Compound I-75

SMILES COCCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1

InChI Key InChIKey=SFTGPJZKXBQVEB-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536496   

TargetB-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429](Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandPNGBDBM536496((S)-3-chloro-5-(1-(2- ((3-chloro-2-fluoro-6- (4-(2...)
Affinity DataKd:  3.70nMAssay Description:This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent