BDBM536495 3-chloro-5-(1-(2-((3- chloro-2-fluoro-6- (pyrrolidin-1-yl)pyridin- 4-yl)amino)-2-oxo- ethyl)-4-oxo-4,6,7,8- tetrahydro-1H-dipyrrolo [1,2-a:2',3'-d]pyrimidin- 3-yl)-2-hydroxy- benzamide::US11242351, Compound I-74

SMILES NC(=O)c1cc(cc(Cl)c1O)-c1cn(CC(=O)Nc2cc(nc(F)c2Cl)N2CCCC2)c2nc3CCCn3c(=O)c12

InChI Key InChIKey=BJZKQPOYFARQTQ-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536495   

TargetB-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429](Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandPNGBDBM536495(3-chloro-5-(1-(2-((3- chloro-2-fluoro-6- (pyrrolid...)
Affinity DataKd:  14.8nMAssay Description:This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent