BDBM536493 (S)-5-(1-(2-((3-chloro- 2-fluoro-6-(2-methyl- 4-(oxetan-3-yl)pipera- zin-1-yl)pyridin-4-yl) amino)-2-oxoethyl)- 4-oxo-4,6,7,8-tetra- hydro-1H-dipyrrolo [1,2-a:2',3'-d]pyrimi- din-3-yl)-2-hydroxy- 3,4-dimethoxy- benzamide::US11242351, Compound I-72

SMILES COc1c(O)c(cc(-c2cn(CC(=O)Nc3cc(nc(F)c3Cl)N3CCN(C[C@@H]3C)C3COC3)c3nc4CCCn4c(=O)c23)c1OC)C(N)=O

InChI Key InChIKey=CNDVZDSPNMUYDC-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536493   

TargetB-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429](Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandPNGBDBM536493((S)-5-(1-(2-((3-chloro- 2-fluoro-6-(2-methyl- 4-(o...)
Affinity DataKd:  85.1nMAssay Description:This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent