BDBM536485 5-(1-(2-((3-chloro-2- fluoro-6-((S)-3- methylmorpholino) pyridin-4-yl)amino)- 2-oxoethyl)-7-methyl- 4-oxo-4,6,7,8- tetrahydro-1H-dipyrrolo [1,2-a:2',3'-d]pyrimidin- 3-yl)-3,4-difluoro-2- hydroxybenzamide::US11242351, Compound I-64

SMILES CC1Cc2nc3n(CC(=O)Nc4cc(nc(F)c4Cl)N4CCOC[C@@H]4C)cc(-c4cc(C(N)=O)c(O)c(F)c4F)c3c(=O)n2C1

InChI Key InChIKey=DYWSSZXFGFURLF-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536485   

TargetB-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429](Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandPNGBDBM536485(5-(1-(2-((3-chloro-2- fluoro-6-((S)-3- methylmorph...)
Affinity DataKd:  27.4nMAssay Description:This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent