BDBM536482 (S)-3-chloro-5-(1-(2- ((3-chloro-6-(2,4- dimethylpiperazin-1- yl)-2-fluoropyridin- 4-yl)amino)-2- oxoethyl)-4-oxo- 4,6,7,8-tetrahydro-1H- dipyrrolo[1,2-a:2',3'-d] pyrimidin-3-yl)-2- hydroxybenzamide::US11242351, Compound I-61

SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1

InChI Key InChIKey=VSGFAZMSYAWCRX-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536482   

TargetB-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429](Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandPNGBDBM536482((S)-3-chloro-5-(1-(2- ((3-chloro-6-(2,4- dimethylp...)
Affinity DataKd:  3.71nMAssay Description:This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent