BDBM536481 (S)-3-chloro-5-(1-(2- ((3-chloro-6-(2,4- dimethylpiperazin-1- yl)-2-fluoropyridin-4- yl)amino)-2-oxoethyl)- 7,7-dimethyl-4-oxo- 4,6,7,8-tetrahydro-1H- dipyrrolo[1,2-a:2',3'-d] pyrimidin-3-yl)-2- hydroxybenzamide::US11242351, Compound I-60

SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2nc2CC(C)(C)Cn2c3=O)c(Cl)c(F)n1

InChI Key InChIKey=LGXWGGZWHGRIBP-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536481   

TargetB-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429](Human)
Ontario Institute For Cancer Research (Oicr)

US Patent
LigandPNGBDBM536481((S)-3-chloro-5-(1-(2- ((3-chloro-6-(2,4- dimethylp...)
Affinity DataKd:  13.4nMAssay Description:This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent