BDBM536210 US11242344, Example 106.2::US11242344, Example 106.4

SMILES CC(C)C(C(=O)N1C[C@H](O)C[C@@H]1C1=NC(=O)[C@](C)(N1)c1ccc(cc1)-c1cccnc1C)c1cc(C)no1

InChI Key InChIKey=WPZOEZCNSSMQBG-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 536210   

LigandPNGBDBM536210(US11242344, Example 106.4 | US11242344, Example 10...)
Affinity DataIC50: 4.00E+5nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM536210(US11242344, Example 106.4 | US11242344, Example 10...)
Affinity DataKd: >1.50E+5nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM536210(US11242344, Example 106.4 | US11242344, Example 10...)
Affinity DataIC50: 2.96E+3nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM536210(US11242344, Example 106.4 | US11242344, Example 10...)
Affinity DataKd:  895nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent