BDBM536202 US11242344, Example 105.2

SMILES CC(C)C(C(=O)N1C[C@H](O)C[C@H]1C1=NC(=O)[C@](C)(N1)c1ccc(cc1)-c1cccnc1)c1cc(C)no1

InChI Key InChIKey=DIXNBDVQUQMYDT-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 536202   

LigandPNGBDBM536202(US11242344, Example 105.2)
Affinity DataIC50: 1.36E+5nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM536202(US11242344, Example 105.2)
Affinity DataKd:  1.13E+5nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent