BDBM536200 2-((4R)-4-Hydroxy-1-(3-methyl-2-(3-methylisoxazol-5-yl)butanoyl) pyrrolidin-2-yl)-5-methyl-5-(4-(pyridin-3-yl) phenyl)-1,5-dihydro-4H-imidazol-4-one::US11242344, Example 105.1

SMILES CC(C)C(C(=O)N1C[C@H](O)C[C@H]1C1=NC(=O)[C@@](C)(N1)c1ccc(cc1)-c1cccnc1)c1cc(C)no1

InChI Key InChIKey=DIXNBDVQUQMYDT-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 536200   

LigandPNGBDBM536200(2-((4R)-4-Hydroxy-1-(3-methyl-2-(3-methylisoxazol-...)
Affinity DataIC50: 3.75E+5nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
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LigandPNGBDBM536200(2-((4R)-4-Hydroxy-1-(3-methyl-2-(3-methylisoxazol-...)
Affinity DataKd:  2.41E+5nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
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