BDBM536174 US11242344, Example 101.3

SMILES CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@@H]1C1=NC(=O)[C@@](C)(N1)c1ccc(Br)cc1)C(C)(C)C

InChI Key InChIKey=BXQUIQWJTNLTHH-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 536174   

LigandPNGBDBM536174(US11242344, Example 101.3)
Affinity DataIC50: 2.00E+5nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent

LigandPNGBDBM536174(US11242344, Example 101.3)
Affinity DataKd:  3.32E+5nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
Go to US Patent