BDBM535690 4-(N-(2- Hydroxyethyl)sulfamoyl)-2-(6- azaspiro[2.5]octan-6-yl)-N-(2-(3,3,3- trifluoropropoxy)pyrimidin-4- yl)benzamide::US11236069, Example 17-1

SMILES OCCNS(=O)(=O)c1ccc(C(=O)Nc2ccnc(OCCC(F)(F)F)n2)c(c1)N1CCC2(CC2)CC1

InChI Key InChIKey=MUQIUFYFVRUYDE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535690   

TargetKinesin-like protein KIF18A [1-467](Human)
Amgen

US Patent
LigandPNGBDBM535690(4-(N-(2- Hydroxyethyl)sulfamoyl)-2-(6- azaspiro[2....)
Affinity DataIC50: 27nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In DepthDetails
US Patent