BDBM535665 (R)-N-(2-(3,3-Difluoroazetidin- 1-yl)-6-methylpyrimidin-4-yl)- 4-((2-hydroxy-1- methylethyl)sulfonamido)-2-(6- azaspiro[2.5]octan-6- yl)benzamide::US11236069, Example 11-76

SMILES C[C@H](CO)S(=O)(=O)Nc1ccc(C(=O)Nc2cc(C)nc(n2)N2CC(F)(F)C2)c(c1)N1CCC2(CC2)CC1

InChI Key InChIKey=JKNPKHOENXUHSI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535665   

TargetKinesin-like protein KIF18A [1-467](Human)
Amgen

US Patent
LigandPNGBDBM535665((R)-N-(2-(3,3-Difluoroazetidin- 1-yl)-6-methylpyri...)
Affinity DataIC50: 20nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In DepthDetails
US Patent