BDBM535634 (S)-4-((2- Hydroxyethyl)sulfonamido)-N- (6-methyl-2-(2- methylmorpholino)pyrimidin-4- yl)-2-(6-azaspiro[2.5]octan-6- yl)benzamide::US11236069, Example 11-45

SMILES C[C@H]1CN(CCO1)c1nc(C)cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC3)CC2)n1

InChI Key InChIKey=POKANPPMADPXNT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535634   

TargetKinesin-like protein KIF18A [1-467](Human)
Amgen

US Patent
LigandPNGBDBM535634((S)-4-((2- Hydroxyethyl)sulfonamido)-N- (6-methyl-...)
Affinity DataIC50: 35nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In DepthDetails
US Patent