BDBM535633 N-(2-((1S,6R)-2- Azabicyclo[4.1.0]heptan-2-yl)- 6-methylpyrimidin-4-yl)-4-((2- hydroxyethyl)sulfonamido)-2- (6-azaspiro[2.5]octan-6- yl)benzamide::US11236069, Example 11-44

SMILES Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC3)CC2)nc(n1)N1CCC[C@@H]2CC12

InChI Key InChIKey=ZSTHRIZNNDNROL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535633   

TargetKinesin-like protein KIF18A [1-467](Human)
Amgen

US Patent
LigandPNGBDBM535633(N-(2-((1S,6R)-2- Azabicyclo[4.1.0]heptan-2-yl)- 6-...)
Affinity DataIC50: 33nMAssay Description:Microtubule-stimulated ATPase activity assay is used to measure KIF18A enzyme activity after treatment with compound. Compounds were 2-fold serially ...More data for this Ligand-Target Pair
In DepthDetails
US Patent