BDBM534122 6-(Azetidin-1-yl)-N-[(5-(tert-butyl)-2-isopropoxyphenyl)sulfonyl]-4-fluorobenzofuran-2-carboxamide::WO2022081807, Example 229

SMILES CC(C)Oc1ccc(cc1S(=O)(=O)NC(=O)c1cc2c(F)cc(cc2o1)N1CCC1)C(C)(C)C

InChI Key InChIKey=KPNREYDNFNQSSR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534122   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandPNGBDBM534122(WO2022081807, Example 229 | 6-(Azetidin-1-yl)-N-[(...)
Affinity DataIC50: 4.79nMAssay Description:Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081807

TargetHistone acetyltransferase KAT6B(Human)
The Broad Institute

WIPO
LigandPNGBDBM534122(WO2022081807, Example 229 | 6-(Azetidin-1-yl)-N-[(...)
Affinity DataIC50: 28nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081807