BDBM533396 US11220509, Example 28::US20240398811, Example 28

SMILES Cc1cc(-c2cnc(NCc3c(F)ccc4occc34)n3cc(nc23)C#N)n(C)n1

InChI Key InChIKey=PIQTYJZWPJPBRT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 533396   

LigandPNGBDBM533396(US11220509, Example 28 | US20240398811, Example 28)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533396(US11220509, Example 28 | US20240398811, Example 28)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM533396(US11220509, Example 28 | US20240398811, Example 28)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present disclosure were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent