BDBM531143 3-((2-((5,5-dimethyl-5,6,7,8-tetrahydro-4H-cyclohepta[b]furan-4-yl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)-2-hydroxy-N,N-dimethylbenzamide::US11208377, Compound 47

SMILES CN(C)C(=O)c1cccc(Nc2c(NC3c4ccoc4CCCC3(C)C)c(=O)c2=O)c1O

InChI Key InChIKey=LOHVVDWKGQWDQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531143   

TargetC-C chemokine receptor type 6(Human)
Allergan

US Patent
LigandPNGBDBM531143(US11208377, Compound 47 | 3-((2-((5,5-dimethyl-5,6...)
Affinity DataIC50: 85nMAssay Description:HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent