BDBM53105 CHEMBL1315054::MLS001164598::N-[(Z)-1-[3-(dimethylamino)propylcarbamoyl]-2-[5-(2-nitrophenyl)-2-furyl]vinyl]-4-methyl-benzamide::N-[(Z)-3-[3-(dimethylamino)propylamino]-1-[5-(2-nitrophenyl)-2-furanyl]-3-oxoprop-1-en-2-yl]-4-methylbenzamide::N-[(Z)-3-[3-(dimethylamino)propylamino]-1-[5-(2-nitrophenyl)furan-2-yl]-3-oxidanylidene-prop-1-en-2-yl]-4-methyl-benzamide::N-[(Z)-3-[3-(dimethylamino)propylamino]-1-[5-(2-nitrophenyl)furan-2-yl]-3-oxoprop-1-en-2-yl]-4-methylbenzamide::N-{1-({[3-(dimethylamino)propyl]amino}carbonyl)-2-[5-(2-nitrophenyl)-2-furyl]vinyl}-4-methylbenzamide::SMR000539729::cid_2131982::jm5b01461, Compound 187

SMILES CN(C)CCCNC(=O)C(\NC(=O)c1ccc(C)cc1)=C\c1ccc(o1)-c1ccccc1[N+]([O-])=O

InChI Key InChIKey=AAVOXWIZJYSGEP-UHFFFAOYSA-N

Data  2 KI  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 53105   

TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53105(N-[(Z)-3-[3-(dimethylamino)propylamino]-1-[5-(2-ni...)
Affinity DataEC50:  3.00E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53105(N-[(Z)-3-[3-(dimethylamino)propylamino]-1-[5-(2-ni...)
Affinity DataEC50:  1.86E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetApoptotic protease-activating factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53105(N-[(Z)-3-[3-(dimethylamino)propylamino]-1-[5-(2-ni...)
Affinity DataIC50: 7.01E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2012
Entry Details
PCBioAssay
TargetApoptotic protease-activating factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53105(N-[(Z)-3-[3-(dimethylamino)propylamino]-1-[5-(2-ni...)
Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2012
Entry Details
PCBioAssay
TargetReplicase polyprotein 1ab(SARS-CoV)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM53105(N-[(Z)-3-[3-(dimethylamino)propylamino]-1-[5-(2-ni...)
Affinity DataIC50: 4.14E+4nMAssay Description:Inhibition of SARS coronavirus recombinant 3C-like protease expressed in Escherichia coli BL21(DE3) after 30 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM53105(N-[(Z)-3-[3-(dimethylamino)propylamino]-1-[5-(2-ni...)
Affinity DataKi:  9.93E+3nMAssay Description:Inhibition of SARS coronavirus recombinant 3C-like protease expressed in Escherichia coli BL21(DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM53105(N-[(Z)-3-[3-(dimethylamino)propylamino]-1-[5-(2-ni...)
Affinity DataKi:  9.93E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed